Antiproliferative Activity of Aloe arborescens Leaf Skin Extracts Tested on Murine Myeloma Cells: Cytological Studies and Chemical Investigations
نویسندگان
چکیده
MTT assays showed an intense antiproliferative activity (80%) of Aloe arborescens leaf skin extracts tested on murine myeloma cells. Bioassay-guided fractionation carried out by TLC allowed the identification of a spot showing antiproliferative activity; HPLC and NMR investigations showed that the TLC spot consisted of aloenin A and aloins A and B. The effects of the leaf extract and of the TLC spot were evaluated both by immunofluorescence techniques in order to test the microtubular array and at the morphological level by SEM and TEM observations. _____________________________________________________________________________________________________________
منابع مشابه
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